Resources and Publications

As one of the foremost experts on ME/CFS, Dr. Montoya has co-authored numerous scientific papers on his research including:

Comparative Analysis of Extracellular Vesicles in Patients with Severe and Mild Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Bonilla H, Hampton D, Marques de Menezes EG, Deng X, Montoya JG, Anderson J, Norris PJ. Front Immunol. 2022 Mar 4;13:841910. doi: 10.3389/fimmu.2022.841910. eCollection 2022. PMID: 35309313

 

Caring for the Patient with Severe or Very Severe Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Montoya JG, Dowell TG, Mooney AE, Dimmock ME, Chu L. Healthcare (Basel). 2021 Oct 6;9(10):1331. doi: 10.3390/healthcare9101331.

 

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Essentials of Diagnosis and Management.

Bateman L, Bested AC, Bonilla HF, Chheda BV, Chu L, Curtin JM, Dempsey TT, Dimmock ME, Dowell TG, Felsenstein D, Kaufman DL, Klimas NG, Komaroff AL, Lapp CW, Levine SM, Montoya JG, Natelson BH, Peterson DL, Podell RN, Rey IR, Ruhoy IS, Vera-Nunez MA, Yellman BP. Mayo Clin Proc. 2021 Nov;96(11):2861-2878. doi: 10.1016/j.mayocp.2021.07.004.

 

Hypothalamic-Pituitary Autoimmunity and Related Impairment of Hormone Secretions in Chronic Fatigue Syndrome.

De Bellis A, Bellastella G, Pernice V, Cirillo P, Longo M, Maio A, Scappaticcio L, Maiorino MI, Bellastella A, Esposito K, Montoya JG.
J Clin Endocrinol Metab. 2021 Nov 19;106(12):e5147-e5155. doi: 10.1210/clinem/dgab429.

 

Plasma proteomic profiling suggests an association between antigen driven clonal B cell expansion and ME/CFS.

 Milivojevic M, Che X, Bateman L, Cheng A, Garcia BA, Hornig M, Huber M, Klimas NG, Lee B, Lee H, Levine S, Montoya JG, Peterson DL, Komaroff AL, Lipkin WI. PLoS One. 2020 Jul 21;15(7):e0236148. doi: 10.1371/journal.pone.0236148. eCollection 2020.

 

Onset Patterns and Course of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.

Chu L, Valencia IJ, Garvert DW, Montoya JG. Front Pediatr. 2019 Feb 5;7:12. doi: 10.3389/fped.2019.00012. eCollection 2019.

 

Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics.

Nagy-Szakal D, Barupal DK, Lee B, Che X, Williams BL, Kahn EJR, Ukaigwe JE, Bateman L, Klimas NG, Komaroff AL, Levine S, Montoya JG, Peterson DL, Levin B, Hornig M, Fiehn O, Lipkin WI. Sci Rep. 2018 Jul 3;8(1):10056. doi: 10.1038/s41598-018-28477-9

 

Deconstructing post-exertional malaise in myalgic encephalomyelitis/ chronic fatigue syndrome: A patient-centered, cross-sectional survey.

Chu L, Valencia IJ, Garvert DW, Montoya JG. PLoS One. 2018 Jun 1;13(6):e0197811. doi: 10.1371/journal.pone.0197811

 

Cortical hypoactivation during resting EEG suggests central nervous system pathology in patients with chronic fatigue syndrome.

Zinn MA, Zinn ML, Valencia I, Jason LA, Montoya JG. Biol Psychol. 2018 Jul;1 36:87-99. doi: 10.1016/j.biopsycho.2018.05.016

 

Value of Circulating Cytokine Profiling During Submaximal Exercise Testing in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.

Moneghetti KJ, Skhiri M, Contrepois K, Kobayashi Y, Maecker H, Davis M, Snyder M, Haddad F, Montoya JG. Sci Rep. 2018 Feb 9;8(1):2779. doi: 10.1038/s41598-018-20941-w.

 

Cytokine signature associated with disease severity in chronic fatigue syndrome patients.

Montoya JG, Holmes TH, Anderson JN, Maecker HT, Rosenberg-Hasson Y, Valencia IJ, Chu L, Younger JW, Tato CM, Davis MM. Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):E7150-E7158. doi: 10.1073/pnas.1710519114. 

 

Fecal metagenomic profiles in subgroups of patients with myalgic encephalomyelitis/chronic fatigue syndrome.

Nagy-Szakal D, Williams BL, Mishra N, Che X, Lee B, Bateman L, Klimas NG, Komaroff AL, Levine S, Montoya JG, Peterson DL, Ramanan D, Jain K, Eddy ML, Hornig M, Lipkin WI. Microbiome. 2017 Apr 26;5(1):44. doi: 10.1186/s40168-017-0261-y.

 

Metagenomic Investigation of Plasma in Individuals with ME/CFS Highlights the Importance of Technical Controls to Elucidate Contamination and Batch Effects.

Miller RR, Uyaguari-Diaz M, McCabe MN, Montoya V, Gardy JL, Parker S, Steiner T, Hsiao W, Nesbitt MJ, Tang P, Patrick DM; CCD Study Group. PLoS One. 2016 Nov 2;11(11):e0165691. doi: 10.1371/journal.pone.0165691. eCollection 2016.

 

Distinct plasma immune signatures in ME/CFS are present early in the course of illness.

Hornig M, Montoya JG, Klimas NG, Levine S, Felsenstein D, Bateman L, Peterson DL, Gottschalk CG, Schultz AF, Che X, Eddy ML, Komaroff AL, Lipkin WI. Sci Adv. 2015 Feb;1(1):e1400121. doi: 10.1126/sciadv.1400121.

 

Right arcuate fasciculus abnormality in chronic fatigue syndrome.

Zeineh MM, Kang J, Atlas SW, Raman MM, Reiss AL, Norris JL, Valencia I, Montoya JG. Radiology. 2015 Feb;274(2):517-26. doi: 10.1148/radiol.14141079. Epub 2014 Oct 29.

 

Randomized clinical trial to evaluate the efficacy and safety of valganciclovir in a subset of patients with chronic fatigue syndrome.

Montoya JG, Kogelnik AM, Bhangoo M, Lunn MR, Flamand L, Merrihew LE, Watt T, Kubo JT, Paik J, Desai M. J Med Virol. 2013 Dec;85(12):2101-9. doi: 10.1002/jmv.23713.

 

Daily cytokine fluctuations, driven by leptin, are associated with fatigue severity in chronic fatigue syndrome: evidence of inflammatory pathology.

Stringer EA, Baker KS, Carroll IR, Montoya JG, Chu L, Maecker HT, Younger JW. J Transl Med. 2013 Apr 9;11:93. doi: 10.1186/1479-5876-11-93.

 

Response to valganciclovir in chronic fatigue syndrome patients with human herpesvirus 6 and Epstein-Barr virus IgG antibody titers.

Watt T, Oberfoell S, Balise R, Lunn MR, Kar AK, Merrihew L, Bhangoo MS, Montoya JG. J Med Virol. 2012 Dec;84(12):1967-74. doi: 10.1002/jmv.23411

 

A multicenter blinded analysis indicates no association between chronic fatigue syndrome/myalgic encephalomyelitis and either xenotropic murine leukemia virus-related virus or polytropic murine leukemia virus.

Alter HJ, Mikovits JA, Switzer WM, Ruscetti FW, Lo SC, Klimas N, Komaroff AL, Montoya JG, Bateman L, Levine S, Peterson D, Levin B, Hanson MR, Genfi A, Bhat M, Zheng H, Wang R, Li B, Hung GC, Lee LL, Sameroff S, Heneine W, Coffin J, Hornig M, Lipkin WI. mBio. 2012 Sep 18;3(5): e00266-12. doi: 10.1128/mBio.00266-12.